Panemunė Castle is a castle on the right bank of the Nemunas River, in Vytėnai, Jurbarkas district, Lithuania.
The initial hill fort of the Teutonic Knights, erected in 1343 was replaced by a castle built in 1604-1610 by a noble Hungarian descent Janusz Eperjesz.
The name “Panemunė“, arose from the former Panemunė Manor that was once here.
Panemunė Castle was not designed to be a stronghold for the defence of the land but a typical, for the beginning of the 17th century, nobleman castle with defensive fittings, residential buildings, and farm buildings.
Panemunė Castle became one of the most beautiful Renaissance-era building in Lithuania.
The castle was reconstructed around 1759 by Giełgud family.
In 2009, a reconstruction of the castle began and was laid out in three phases, which phase can last around three years to complete, the project involved the restoration of one of the castle building to be restored, two defensive towers and replace the roof coverings and windows, The project is funded by the EU Structural Funds.